Juvederm and Restylane are the two most popular hyaluronic acid lip fillers on the market. Both are considered safe and effective, and can produce natural-looking results. Both are available with or without lidocaine to reduce pain. Restylane-L, Juvederm, and Belotero are all dermal fillers that are commonly used for facial wrinkles, asymmetry, and volume loss.
However, not all dermal fillers are intended for use as lip fillers. Calcium hydroxylapatite (CaHA) fillers have received FDA approval for certain types of facial filler injections, but not as lip fillers. Poly-L-lactic acid (PLLA) is not reversible, so it's best to work with board-certified providers who have received comprehensive dermal filler training and certification. Studies have shown that combination treatments of platelet-rich plasma (PRP) with dermal fillers can provide greater longevity of results.
Dermal fillers are primarily created from hyaluronic acid, a natural substance found in the skin. Hyaluronic acid gel lip fillers are widely regarded as the best for lip augmentation, as they have been shown to produce consistent results, are readily available, and carry a lower risk of adverse reactions compared to other fillers.